AN UNBIASED VIEW OF DIAZEPAM BNF

Diazepam is N-demethylated by CYP3A4 and 2C19 on the Lively metabolite N-desmethyldiazepam, and is also hydroxylated by CYP3A4 towards the active metabolite temazepam. N-desmethyldiazepam and temazepam are both of those even further metabolized to oxazepam. Temazepam and oxazepam are mainly removed by glucuronidation.Small improvements in EEG desig